20 mg Adult Prevention of NSAID-induced gastroduodenal ulcer 20 mg/day.
Adult & adolescent ≥12 yr Symptomatic GERD 20 mg/day for 2-4 wk.
Long-term management & prevention of relapse in reflux oesophagitis Maintenance dose 20 mg/day. May increase up to 40 mg/day in case of relapse.
40 mg Adult Eradication of H. pylori in combination w/ antibiotics 40 mg bd w/ amoxicillin 1000 mg bd & clarithromycin 500 mg bd OR 40 mg bd w/ metronidazole 400-500 mg bd (or tinidazole 500 mg bd) & clarithromycin 250-500 mg bd OR 40 mg bd w/ amoxicillin 1000 mg bd & metronidazole 400-500 mg bd.
Gastric ulcer 40 mg/day for 4 wk.
Zollinger-Ellison syndrome & other pathological hypersecretory conditions Initially 80 mg in 2 divided doses.
Adult & childn ≥12 yr Reflux oesophagitis 40 mg/day for 4 wk.