Onychomycosis/tinea fingernail 200 mg bid for 1 wk each mth for 2 mth (1 wk on & 3 wk off).
Toenail w/ or w/o fingernail involvement 200 mg bid for 1 wk each mth for 3 mth (1 wk on & 3 wk off) or 200 mg once daily for 12 wk.
Dermatomycoses Tinea corporis & cruris 200 mg once daily for 7 days or 100 mg bid for 2 days or 100 mg once daily for 15 days.
Plantar tinea pedis & palmar tinea manuum 100 mg once daily for 30 days or 200 mg bid for 7 days.
Tinea capitis 200 mg once daily for 2-4 wk.
Pityriasis (tinea versicolor) Treatment: 400 mg as single dose or 400 mg/day for 3 days or 200 mg/day for 5-7 days. Prophylaxis: 200 mg bid 1 day/mth for 6 consecutive mth.
Seborrheic dermatitis Treatment: 200 mg/day for 7 days. Prophylaxis: 200 mg once daily for 1st 2 days of each mth.
Vulvovag candidiasis Acute: 200 mg bid for 1 day or 200 mg once daily for 3 days. Recurrent: Acute regimen followed by 200 mg once daily on 1st day of menses for 6 cycles.
Oral candidiasis 100 mg once daily for 15 days.
Patient w/ AIDS/neutropenia 200 mg once daily for 15 days.
Aspergillosis (pulmonary & extrapulmonary) Usual dose: 200-400 mg daily (200 mg once daily or bid) for min of 3 mth & until resolution of active fungal infection. Life-threatening situations: 600 mg daily (200 mg bid) for 1st 3 days as loading dose followed by usual dose.
Histoplasmosis/blastomycosis 200 mg once daily for a min of 3 mth & until resolution of active fungal infection. Dose may be increased in 100-mg increments to max of 400 mg daily.
Sporotrichosis 200-400 mg daily (200 mg once daily or bid) for a min of 3 mth & until resolution of active fungal infection.
Cryptococcosis (other than meningeal) Treatment: 200 mg bid. Maintenance: 200 mg bid.
Cryptococcal meningitis Prophylaxis in AIDS patient 200 mg once daily.
Coccidioidomycosis 200 mg bid for 6 wk.
Paracoccidioidomycosis 100 mg once daily for 6 mth.
Chromomycosis 100-200 mg once daily for 3-6 mth.
Other systemic mycoses 200 mg once daily or bid until resolution of active symptoms.
Cryptococcal meningitis Lifelong therapy may be indicated.
Neutropenia Treatment (empiric): 200 mg bid following 14 days of IV treatment until neutropenia resolves. Prophylaxis (primary or secondary): 200 mg daily.
AIDS Prophylaxis/prevention of fungal infection: 200 mg daily.
Oculomycoses 200 mg once daily or bid until resolution of active fungal infection.
Immunosuppressant therapy/chemotherapy/transplant recipient 400 mg until immune system recovery.
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