Celsus Prednisolone Acetate

Prednisolone acetate.

Each mL contains Prednisolone Acetate 10 mg.
Excipients/Inactive Ingredients: Edetate Disodium, Dried Sodium Phosphate, Polysorbate 80, Glycerin, Citric Acid (pH adjuster) and Purified Water.
Viscosity Agent: Hydroxypropyl Methylcellulose.
Preservative: Benzalkonium Chloride.

Pharmacology: Inhibition of inflammatory response to inciting agents of mechanical, chemical or immunological nature. It inhibits edema, fibrin deposition, capillary dilation, and phagocytic migration deposition of collagen and scar formation.

For the treatment of various inflammatory and allergic ocular conditions such as allergic, catarrhal, and vernal conjunctivitis, inflammatory keratitis, iritis and other inflammatory disorders of the anterior segment of the globe.

Two drops every four hours or as prescribed by the physician.

In most viral eye diseases, tuberculous and fungal disease and sensitivity to any component of the formulation.

Adverse reactions include, in decreasing order of frequency, elevation of intraocular pressure (IOP) with possible development of glaucoma and infrequent optic nerve damage, posterior subcapsular cataract formation, and delayed wound healing. Although systemic effects are extremely uncommon, there have been rare occurrences of systemic hypercorticoidism after use of topical steroids.
Corticosteroid-containing preparations have also been reported to cause acute anterior uveities and perforation of the globe. Keratitis, conjunctivitis, corneal ulcers, mydriasis, conjunctival hyperemia, loss of accommodation and ptosis have occasionally been reported following use of corticosteroids.
The development of secondary ocular infection (bacterial, fungal and viral) has occurred. Fungal and viral infections of the cornea are particularly prone to develop coincidentally with long-term applications of steroid. The possibility of fungal invasions should be considered in any persistent corneal ulceration where steroid treatment has been used.

Amphotericin may increase hypokalemia. May decrease effect of oral hypoglycemics, insulin, diuretics, potassium supplements. May increase digoxin toxicity (due to hypokalemia). Hepatic enzyme inducers may decrease effect. Live virus vaccines may potentiate virus replication, increase vaccines side effects, decrease patient's antibody response to vaccine. LAB VALUES: May decrease calcium, cholesterol, lipids, glucose, sodium, amylase.

Keep tightly closed after use. Store at temperatures not exceeding 30°C.

Eye Corticosteroids

S01BA04 - prednisolone ; Belongs to the class of corticosteroids. Used in the treatment of inflammation of the eye.

Rx