Nasatapp No-Drowse

Paracetamol, phenylephrine hydrochloride.

Each tablet contains: Paracetamol, USP 500 mg, Phenylephrine hydrochloride 25 mg.

This medicine contains paracetamol and phenylephrine hydrochloride. Phenylephrine HCl, a nasal decongestant, clears obstructed air passages and nasal sinuses due to congestion making breathing easier. It also reduces postnasal drip. Paracetamol is an effective fever reducer and pain reliever.

This medicine is used for the relief of clogged nose, postnasal drip, headache, body aches, and fever associated with the common cold, sinusitis, flu, and other minor respiratory tract infections. It also helps decongest sinus openings and passages.

Adults and children 12 years and older: Orally, 1 tablet every 6 hours, or as prescribed by the physician.
Missed Dose: If the patient misses a dose, just take the next dose if still needed for the condition being treated, and the subsequent doses at the recommended time or schedule (i.e. every 6 hours).
Do not double the dose.

Signs & Symptoms: Phenylephrine hydrochloride: Increased blood pressure, headache, seizures, palpitation, paresthesia (sensation of tingling, pricking, or numbness of the skin), vomiting, cerebral hemorrhage (bleeding from a ruptured blood vessel in the brain).
Paracetamol: Overdosage of paracetamol usually involves 4 phases with the following signs and symptoms: I. Eating disorder, nausea, vomiting, malaise, and excessive sweating.
II. Right upper abdominal pain or tenderness, liver enlargement which may be characterized by abdominal discomfort of "feeling full", elevated bilirubin and liver enzyme concentrations, prolongation of prothrombin time, and occasionally decreased urine output.
III. Eating disorder, nausea, vomiting, and malaise recur and signs of liver failure (e.g., jaundice) and possibly kidney failure and cardiomyopathy (disorder of the heart muscle) may develop.
IV. Recovery or progression to fatal complete liver failure.
If Taken More Than the Recommended Dosage: If the patient has taken more than the recommended dosage, consult a doctor or contact a poison control center right away, even if the patient seems well, because of the risk of delayed, serious liver damage. Quick medical attention is important for adults as well as for children even if the patient does not notice any signs or symptoms.

If the patient is allergic to any ingredient in the product.
If the patient has high blood pressure or severe heart disease unless recommended by a doctor.
If the patient has anemia, kidney or liver disease unless recommended by a doctor.
If the patients is pregnant or breastfeeding.

Liver Warning: This product contains paracetamol.
Severe liver damage may occur if the patient takes: more than 4g of paracetamol in 24 hours, which is the maximum daily amount; with other medicines containing paracetamol (or acetaminophen); 3 or more alcoholic drinks everyday while using this product.
Do not use with any other medicine containing paracetamol (prescription or nonprescription). If the patient is not sure whether a medicine contains paracetamol, ask a doctor.
Ask a doctor before use if the patient has liver disease.
Ask a doctor before use if the patient is taking warfarin, a blood thinning medicine.
Do not take more than the recommended dose.
Consult a doctor: Before taking this medication, tell the doctor if the patient has: High blood pressure or any type of heart problems, glaucoma, thyroid problems, diabetes, liver or kidney disease, and enlarged prostate, bladder problems or difficulty urinating.
Stop use and ask a doctor if: Fever gets worse or lasts more than 3 days; New symptoms occur.

Phenylephrine HCl may cause tremor (muscle shaking), restlessness, anxiety (feeling of uneasiness), insomnia/sleeplessness, nervousness, dizziness, increased blood pressure, palpitation, arrhythmia (irregular heart beat), weakness, respiratory distress (noisy, congested breathing), and pallor.
Paracetamol, when taken within the recommended dose and duration of treatment, has low incidence of undesirable effects. Skin rashes and minor stomach and intestinal disturbance have been reported.

Do not use this product together with sympathomimetic agents (e.g. epinephrine, etc.) and general anesthetics (e.g. halothane, etc.) because of the possibility for increased toxicity.
Concurrent administration with medicines for depression (e.g. amitriptyline, imipramine, sertraline, moclobemide, etc.) may result in hypertensive crisis (sudden, severe increase in blood pressure that can lead to stroke).
Taking an adrenergic blocking agent (e.g. phenothiazine drugs, phentolamine, propranolol, etc.) before the administration of this product may decrease the effect of phenylephrine.
Medicine which stimulates the enzyme responsible for the metabolic activation of paracetamol such as medicines for convulsion (e.g. phenobarbital, etc.) may increase susceptibility to the harmful effects to the liver.
Warfarin, a blood thinning medicine; an increase in the International Normalized Ratio (INR), which may serve as a sign of increased risk of bleeding, may be observed when using paracetamol and warfarin at the same time. Paracetamol increases the anticoagulation effect of warfarin.
Tell the doctor about the other medicines the patient is taking, especially other medicines for cough, cold, allergy, pain or fever.

Store at temperatures not exceeding 30°C.

Cough & Cold Preparations

N02BE51 - paracetamol, combinations excl. psycholeptics ; Belongs to the class of anilide preparations. Used to relieve pain and fever.

Non-Rx