Each 5 mL (1 teaspoonful) contains: Thiamine Hydrochloride (Vitamin B1) 100 mg, Pyridoxine Hydrochloride (Vitamin B6) 5 mg, Cyanocobalamin (Vitamin B12) 50 mcg.
VITAMIN B1 + B6 + B12 (Polynerv Syrup) is a high-dose B-complex formulation which is essential for body growth since it contains vitamins B1, B6 and B12.
These major vitamins are frequently lacking in unbalanced diets. Even children who take substantial amounts of the B-complex vitamin in the diet may still suffer from deficiency disorders due to use of antibiotics and certain drugs which interfere with the absorption or utilization of B vitamins (i.e. isoniazid, phenothiazines, theophylline).
Absorption of the B-complex vitamins may also be impaired due to prolonged diarrhea.
Normal cellular activities depend on the availability of biochemical energy derived mainly from the food nutrients. VITAMIN B1 + B6 + B12 (Polynerv Syrup) functions as coenzymes which stimulate the various metabolic processes that produce the energy to fuel the cellular activities of the body. The metabolic events in which vitamins B1 + B6 + B12 play dominant roles as cofactors make possible the conversion of food nutrients (carbohydrates, fats and proteins) into utilizable substances to form the different body compounds and tissues.
As coenzymes, VITAMIN B1 + B6 + B12 (Polynerv Syrup) stimulate the various cellular reactions which transform nutrients from food into energy which is used to convert food nutrients into utilizable substances for body growth and repair.
THIAMINE (Vitamin B1), as a cofactor of carbohydrate metabolism, ensures the efficient production of energy from glucose (the body's chief source of energy) and the conversion of glucose into other metabolites such as ribose, a major component of DNA.
Glucose supplies the basic nutritional needs of the nervous system. The cells of the central nervous system depend entirely or almost exclusively on glucose as its energy source.
Independent of its coenzyme function, vitamin B1 acts as a modulator in neuromuscular transmission.
Pyridoxal phosphate plays a key role in the metabolism of amino acids, which is needed for cellular growth and repair, thus necessary in the formation of the body tissues. Specifically, it helps in the biosynthesis of porphyrin needed for the formation of blood elements.
It is also involved in the biosynthesis of neurotransmitters such as serotonin, GABA, norepinephrine which are all important regulatory substances in the nervous system.
COBALAMIN (Vitamin B12) functions as a coenzyme in the synthesis of nucleic acids. It is necessary for the formation and maturation of the red blood cells. It acts as a coenzyme in the conversion of methylmalonyl coA, necessary in the formation of myelin sheath of the nervous tissues. High doses of vitamins B6 and B12 supplementation also provide a good adjunct in the therapeutic management of many forms of anemia especially megaloblastic anemia.
As the well known functions of VITAMIN B1 + B6 +B12 (Polynerv Syrup) are directed towards the CNS, the purported actions of high doses revolve around the central nervous system.
Optimum nutrition of the nervous tissue is a must in the management of diseases causing malfunctioning of the nervous system.
If the neuronal cells are deprived of the basic nutritional needs, the impaired neurophysiologic functions will disturb further the metabolic activities of other organs. The high doses of vitamins B1, B6 and B12 therefore help maintain the normal functioning of the nervous system.
The B-complex vitamins, by virtue of their biological functions as metabolic activators, provide a natural therapeutic support in the management of disorders arising from increased tissue demands. They are also indicated in situations when there is increased body requirement for energy as in growth, strenuous physical activities, stress during illnesses such as hypermetabolic states and infectious diseases.
VITAMIN B1 + B6 + B12 (Polynerv Syrup) provides support in conditions where the requirements for B-complex vitamins are increased (as in growth, physiologic stress, decreased resistance to infection and chronic illnesses, metabolic disorders and in certain diseases of the digestive tract and nervous system). It can also be given before and after surgical procedures.
VITAMIN B1 + B6 + B12 (Polynerv Syrup) is indicated for the prevention and treatment of deficiency disorders arising from poor dietary intake, impaired B-complex vitamins absorption or utilization of B group vitamins (i.e. isoniazid, phenothiazines and phenytoin).
As a nutritional supplement to promote appetite and weight gain.
1-2 years old: 1 mL daily.
3-6 years old: 5 mL (1 teaspoonful) daily.
7-12 years old: 10 mL (2 teaspoonfuls) daily.
Protect from light.
Store at temperatures not exceeding 30°C.
A11DB - Vitamin B1 in combination with vitamin B6 and/or vitamin B12 ; Used as dietary supplements.
Polynerv Syrup syr
120 mL x 1's (P191.86/bottle)
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