Immediate hypersensitivity reactions. Patients predisposed to glaucoma; insufficiently controlled DM, recent MI, severe organic heart or vascular disorders, hyperthyroidism, pheochromocytoma, risk of narrow-angle glaucoma, prostatic hypertrophy or bladder-neck obstruction; hypokalemia; cystic fibrosis; acute, rapidly worsening dyspnea. Avoid contact w/ eyes. Not to be mixed w/ other drugs in same nebulizer. Pregnancy & lactation.
Side effects may be increased w/ other β-adrenergics & anticholinergics. β-agonist induced hypokalemia may be increased w/ xanthine derivatives, glucocorticosteroids & diuretics. May increase susceptibility to arrhythmias w/ digoxin. Potentially serious reduction in bronchodilator effects w/ β-blockers. β-adrenergic agonists action may be enhanced w/ MAOIs or TCAs. Susceptibility to CV effects of β-agonists may be increased w/ halogenated hydrocarbon anaesth eg, halothane, trichloroethylene, enflurane.
R03AL02 - salbutamol and ipratropium bromide ; Belongs to the class of combination of adrenergics with anticholinergics, that may also include a corticosteroid. Used in the treatment of obstructive airway diseases.
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