Orthostatic hypotension. Examine patient to exclude presence of other conditions producing similar symptoms as benign prostatic hyperplasia prior to therapy. Perform digital rectal exam & determine PSA prior to treatment & regularly afterwards. Intraoperative floppy iris syndrome. Not recommended in patients scheduled for cataract or glaucoma surgery. Not to be given in combination w/ strong CYP3A4 inhibitors in patients w/ poor metaboliser CYP2D6 phenotype. Concomitant use w/ strong & moderate CYP3A4 inhibitors. Contains lactose; not to be taken by patients w/ galactose intolerance, Lapp lactase deficiency or glucose-galactose malabsorption. May affect ability to drive & use machines. Severe renal impairment (CrCl <10 mL/min). Not indicated for women. Childn <18 yr.
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