Treatment of susceptible infections including gonorrhea, otitis media, pharyngitis, lower resp tract infections eg, bronchitis & UTI.
Dosage/Direction for Use
FC tabAdult 400 mg once daily or 200 mg 12 hrly. Uncomplicated cervical/urethral gonococcal infections 400 mg as single dose. Childn 8 mg/kg/day as single dose or 4 mg/kg 12 hrly. Typhoid 20 mg/kg/day in 2 divided doses for 10 days. S. pyogenes infections 20 mg/kg/day as single dose for 10 days. Susp/dropsChildn >6 mth (<50 kg) 8 mg/kg daily or 4 mg/kg 12 hrly.
Administration
May be taken with or without food: May be taken w/ food or milk to reduce GI discomfort.
Contraindications
Hypersensitivity to cefixime or other cephalosporins. Renal impairment (CrCl <60 mL/min).
Special Precautions
Hypersensitivity to penicillins. History of allergy. Renal impairment. Avoid prolonged use. Discontinue use if diarrhea occurs. May interfere w/ Jaffe's method of measuring creatinine conc & may produce falsely high values. False +ve direct Coombs' test. False +ve reaction for glucose in urine w/ Benedict's or Fehling's soln or copper sulfate test. Pregnancy & lactation.
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