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Indications/Uses
Treatment & prophylaxis of acute hyperuricaemia to prevent acute renal failure in patients w/ haematological malignancy w/ high tumour burden & at risk of rapid tumour lysis or shrinkage at chemotherapy initiation.
Dosage/Direction for Use
IV Recommended dose: 0.2 mg/kg daily as a once daily 30 min infusion. Treatment duration: May be up to 7 days.
Contraindications
Hypersensitivity to rasburicase or uricases. G6PD deficiency & other cellular metabolic disorders known to cause haemolytic anaemia.