1st line treatment of HTN as monotherapy or in combination w diuretics, α-blockers, β-blockers or an ACE inhibitors. Symptomatic treatment of chronic stable angina or confirmed or suspected vasospastic (Prinzmetal's) angina as monotherapy or in combination w/ antianginal drugs.
Dosage/Direction for Use
Adult Initially 5 mg once daily, may be increased to a max dose of 10 mg once daily.
Administration
May be taken with or without food.
Contraindications
Hypersensitivity to amlodipine or to dihydropyridine derivatives. Severe hypotension; shock (including cardiogenic shock); obstruction of the outflow tract of left ventricle (eg, high grade aortic stenosis); haemodynamically unstable heart failure after acute MI.
Special Precautions
Severe heart failure (NYHA grade III & IV), CHF; hepatic impairment. May affect ability to drive or operate machinery. Pregnancy & lactation. Childn. Elderly.
C08CA01 - amlodipine ; Belongs to the class of dihydropyridine derivative selective calcium-channel blockers with mainly vascular effects. Used in the treatment of cardiovascular diseases.
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