Oedema due to cardiac, hepatic (ascites) or renal disease; burns. Acute cardiac insufficiency especially in pulmonary oedema. Reduce urinary output due to gestosis. In addition to other antihypertensives for hypertensive crisis. Supportive measures in brain oedema. To support forced diuresis in poisoning.
IM/IV Adult & adolescent ≥15 yr Initially 20-40 mg. If diuretic effect is not satisfactory, may be stepwise increased at 2-hrly interval by 20 mg each time until satisfactory diuresis is obtained. Give individual dose once daily to bid. Acute pulmonary oedema Initially 40 mg IV. Inj further dose of 20-40 mg after 20 min depending on patient's condition. Forced diuresis Give 20-40 mg in addition to infusion of electrolyte soln. Childn <15 yr & infant Life-threatening conditions 1 mg/kg up to max of 20 mg daily.
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