Hypersensitivity. Infection or severe inflammation at joint cavity. Disease or infection of skin near the inj site. Liver disease or prior history of liver disease.
Avoid intravascular, extra-articular inj or inj in the synovial tissues. Administer after removal of severely inflamed joints caused by deformative OA. Avoid strenuous exercise or action leading to joint pain of knee up to 48 hr after administration. Accurately inj into articular cavity. Remove articular fluid by puncturing prior to administration. Concomitant use w/ 4th grade ammon salt eg, benzalkonium Cl & chlorhexidine. Inj site should be sterilized prior to administration. Pregnancy & lactation.
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