Medi-α

Medi-α

alfacalcidol

Manufacturer:

Mega Lifesciences

Distributor:

Zuellig Pharma
Full Prescribing Info
Contents
Alfacalcidol.
Description
Each softgel capsule contains Alfacalcidol 0.25 micrograms.
Action
Alfacalcidol or 1-α-hydroxyvitamin D3 is one of vitamin D analogue. Alfacalcidol is rapidly converted in liver to 1,25-dihydroxyvitamin D3 {1,25-(OH)2D3}, the metabolite of vitamin D3 which acts as a regulator of calcium and phosphate metabolism.
Impaired endogenous production of 1,25-dihydroxyvitamin D3 by the kidneys appears to contribute to the disturbances in mineral metabolism found in several disorders, including renal bone disease, hypoparathyroidism and vitamin D-dependent rickets. These disorders require high doses of vitamin D for their correction.
Indications/Uses
Osteoporosis.
Renal osteodystrophy.
Hypoparathyroidism.
Hyperparathyroidism with bone disease.
Nutritional and malabsorptive rickets and osteomalacia.
Hypophosphatemic vitamin D-resistant rickets and osteomalacia.
Dosage/Direction for Use
Initial dose: Adults & children >20 kg body weight: 0.5-1 μg/day.
<20 kg body weight: 0.05 μg/kg/day.
The dosage of Medi-α 0.25 should be adjusted thereafter to avoid hypercalcemia according to the biochemical response.
Contraindications
Hypercalcemia, Hypermagnesemia.
Hypersensitivity to Vitamin D or its analogues.
Use In Pregnancy & Lactation
If the patient is pregnant or breastfeeding, inform the physician prior to the commencement of therapy with this medicine.
Side Effects
Hypercalcemia.
Storage
Store in a dry place below 25°C for Alu-Alu blister and below 30°C for PVC/PVDC-Alu blister.
MIMS Class
Agents Affecting Bone Metabolism
ATC Classification
A11CC03 - alfacalcidol ; Belongs to the class of vitamin D and analogues. Used as dietary supplements.
Presentation/Packing
Form
Medi-α soft-gelatin cap 0.25 mcg
Packing/Price
6 × 10's
Form
Medi-α soft-gelatin cap 0.5 mcg
Packing/Price
3 × 10's
Register or sign in to continue
Asia's one-stop resource for medical news, clinical reference and education
Already a member? Sign in
Register or sign in to continue
Asia's one-stop resource for medical news, clinical reference and education
Already a member? Sign in