Prevention of urotoxic effects of oxazaphosphorines.
Dosage/Direction for Use
AdultIV inj Per dose: 20% of dose of oxazaphosphorine, administered at time zero (time of administration of oxazaphosphorine) repeated after 4 & 8 hr. W/ continuous oxazaphosphorine infusion: 20% of the oxazaphosphorine dose given as bolus inj at time zero, followed by continuous infusion of Uromitexan of up to 100% of the initial oxazaphosphorine dose. Continue infusion for a further 6-12 hr after the end of the oxazaphosphorine administration.
Special Precautions
Protective effect applies only to the urinary tract.
Adverse Reactions
GI effects, headache, malaise, skin rash. Allergic symptoms (rare).
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