Xenetix Dosage & Drug Information

Concise Prescribing Info

Contents

Per 300 mg Iobitridol 65.81 g/100 mL (iodine 30 g/100 mL). Per 350 mg Iobitridol 76.78 g/100 mL (iodine 35 g/100 mL)

Indications/Uses

Listed in Dosage.

Dosage/Direction for Use

300-mgI/mL IV urography Fast inj: 1.2 mL/kg (50-100 mL); slow inj: 1.6 mL/kg (100 mL). CT scan Brain: 1.4 mL/kg (20-100 mL); whole body: 1.9 mL/kg (20-150 mL). IV digital subtraction angiography 1.7 mL/kg (40-270 mL). Arteriography Brain:1.8 mL/kg (42-210 mL); lower limbs: 2.8 mL/kg (85-300 mL). Angiocardiography 1.1 mL/kg (70-125 mL). 350-mgI/mL IV urography 1 mL/kg (50-100 mL). CT scan Brain: 1 mL/kg (40-100 mL); whole body: 1.8 mL/kg (90-180 mL). IV digital subtraction angiography 2.1 mL/kg (95-250 mL). Arteriography Peripheral: 2.2 mL/kg (105-205 mL); lower limbs: 1.8 mL/kg (80-190 mL); abdominal 3.6 mL/kg (155-330 mL). Angiocardiography Adult 1.9 mL/kg (65-270 mL). Childn 4.6 mL/kg (10-130 mL).

Contraindications

Myelography.

Special Precautions

History of allergy eg, hives, asthma, hay fever, eczema, various food & drug allergies. Dehydration. Severe liver or kidney failure. Maintain abundant urine output in patients w/ kidney failure, DM, myeloma or hyperuricemia & atheromatous patients. Concomitant w/ β-blockers. Pregnancy & lactation. Infants & young childn. Elderly.

Adverse Reactions

Cutaneous, resp, neurosensory, GI & CV isolated disorders. Shock &/or circulatory arrest. Hot feeling.

View ADR Monitoring Form

Drug Interactions

Diuretics, metformin, β-adrenergic blocking agents.

MIMS Class

Radiographic & Diagnostic Agents

ATC Classification

V08AB11 - iobitridol ; Belongs to the class of watersoluble, nephrotropic, low osmolar preparations used as X-ray contrast media.

Thai FDA Category

Presentation/Packing

Form

Xenetix inj iobitridol 300 mg iodine/mL

Packing/Price

100 mL x 1's;50 mL x 1's

Form

Xenetix inj iobitridol 350 mg iodine/mL

Packing/Price

100 mL x 1's;50 mL x 1's

Xenetix

Manufacturer:

Guerbet

Distributor:

Pacific Healthcare