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Chỉ định và Liều dùng
Vaginal
Cervicitis, Vaginitis Adult: As supp: Insert 1 supp deep into vagina every other day at bedtime. Treatment duration depends on severity of condition.
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Thận trọng
Pregnancy and lactation.
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Tác dụng không mong muốn
Significant: Local irritation.
Reproductive system and breast disorders: Vaginal dryness, vaginal discharge. |
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Thông tin tư vấn bệnh nhân
Avoid sexual intercourse during and 7 days after treatment. Avoid use of irritant soap during treatment. Not recommended for use during menstruation.
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Tác dụng
Description:
Mechanism of Action: Policresulen is an organic acid with a topical healing effect. It promotes haemostasis by enabling blood protein coagulation and allowing contraction of muscle fibres of small calibre blood vessels, and chemical debridement through interaction with devitalised plasma membrane phospholipid molecules, thus causing denaturation of cellular proteins allowing for their removal. Its acidity and coagulating properties provide antimicrobial effects against staphylococcus spp, streptococcus spp, and Candida albicans. Synonym: Metacresolsuphonic acid-formaldehyde Pharmacokinetics: Excretion: Elimination half-life: 4-5 hours. |
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Đặc tính
 Source: National Center for Biotechnology Information. PubChem Compound Summary for CID 3050404, Policresulen. https://pubchem.ncbi.nlm.nih.gov/compound/Policresulen. Accessed Apr. 27, 2021. |
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Bảo quản
Store below 25°C. Protect from light.
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Phân loại MIMS
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Phân loại ATC
G01AX03 - policresulen ; Belongs to the class of other antiinfectives and antiseptics. Used in the treatment of gynecological infections.
D08AE02 - policresulen ; Belongs to the class of phenol and derivatives antiseptics. Used in the treatment of dermatological diseases. |
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Tài liệu tham khảo
Anon. Policresulen. Lexicomp Online. Hudson, Ohio. Wolters Kluwer Clinical Drug Information, Inc. https://online.lexi.com. Accessed 13/04/2021. Buckingham R (ed). Policresulen. Martindale: The Complete Drug Reference [online]. London. Pharmaceutical Press. https://www.medicinescomplete.com. Accessed 13/04/2021.
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