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Chỉ định và Liều dùng
Oral
Diabetic neuropathy Adult: 600 mg daily. May also be given via IV admin.
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Cách dùng
Should be taken on an empty stomach. Take 30 min before meals. Swallow whole, do not chew/crush.
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Thận trọng
Pregnancy, lactation. Monitor blood glucose and adjust diabetic medication accordingly. May cause insulin autoimmune syndrome in diabetics.
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Tác dụng không mong muốn
Allergic reactions such as skin rash, nausea, hypoglycemia.
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Tác dụng
Description:
Mechanism of Action: Thioctic acid, or α-lipoic acid, is used for its antioxidant effects in the treatment of diabetic neuropathy. It has been tried in the treatment of liver dysfunction and in subacute necrotising encephalopathy. Thioctic acid and its reduced metabolite form a redox couple and may scavenge a wide range of reactive oxygen species. Pharmacokinetics: Distribution: Cross the blood brain barrier. |
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