Depression Differential Diagnosis

Last updated: 11 June 2024

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Differential Diagnosis

The signs and symptoms of depression can overlap with the clinical presentation of psychiatric and general medical disorders such as: 

  • Adjustment disorder with depressed mood 
  • Attention-deficit hyperactivity disorder 
  • Bipolar disorder
  • Borderline personality disorder
  • Burnout 
  • Schizophrenia and schizoaffective disorder
  • Other medical conditions: 
    • Adrenal insufficiency
    • Huntington disease 
    • Hypercortisolism
    • Hypothyroidism 
    • Mononucleosis 
    • Multiple sclerosis 
    • Obstructive sleep apnea 
    • Parkinson’s disease 
    • Stroke 
    • Traumatic brain injury
    • Vitamin B12 insufficiency