Sign Out
Symptoms and signs of overdose: Gastrointestinal symptoms and disturbance of the fluid and electrolyte balances may be evident. Amoxycillin crystalluria, in some cases leading to renal failure, has been observed (see Precautions).
Convulsions may occur in patients with impaired renal function or in those receiving high doses.
Amoxycillin has been reported to precipitate in bladder catheters, predominantly after intravenous administration of large doses. A regular check of patency should be maintained (see Precautions).
Treatment of intoxication: Gastrointestinal symptoms may be treated symptomatically, with attention to the water/electrolyte balance.
Amoxycillin/clavulanic acid can be removed from the circulation by haemodialysis.
375 mg tablet & 156 mg syrup: Children: A prospective study of 51 paediatric patients at a poison control centre suggested that overdosages of <250 mg/kg of amoxycillin are not associated with significant clinical symptoms and do not require gastric emptying.
