Nasal airway infection should be appropriately treated. After nasal surgery, healing must have occurred before use. Caution in patients who may be susceptible to candida infections (eg, diabetics). Reports of systemic effects particularly at high doses prescribed for prolonged periods. Use of excessive doses may cause HPA suppression, reduction in bone density & retardation of growth rate in adolescents & childn. Be alert for evidence of systemic effects including ocular changes.