Ferinject

Ferinject

ferric carboxymaltose

Manufacturer:

Vifor

Distributor:

Zuellig
/
Agencia Lei Va Hong
Concise Prescribing Info
Contents
Ferric carboxymaltose
Indications/Uses
Treatment of Fe deficiency when oral Fe prep are ineffective or cannot be used.
Dosage/Direction for Use
IV Individualised dose based on body wt & Hb level. A single Ferinject administration should not exceed 15 mg Fe/kg body wt (for IV inj) or 20 mg Fe/kg body wt (for IV infusion), but should not exceed 1,000 mg of Fe (20 mL Ferinject). Max recommended cumulative dose: 1,000 mg Fe (20 mL Ferinject) per wk. Patient w/ haemodialysis-dependent CKD Single max daily dose: 200 mg Fe.
Contraindications
Hypersensitivity to ferric carboxymaltose or other parenteral Fe prep. Non-Fe deficiency anaemia eg, other microcytic anaemia. Fe overload or utilisation disturbances.
Special Precautions
Can cause hypersensitivity reactions. If hypersensitivity reactions or signs of intolerance occur during administration, immediately stop treatment. Must not be administered by SC or IM route. Reports of symptomatic hypophosphataemia leading to osteomalacia & fractures requiring clinical intervention including surgery. Monitor serum phosphate in patients who receive multiple administrations at higher doses or long-term treatment & those w/ existing risk factors for hypophosphataemia. Caution in case of acute or chronic infection, asthma, eczema or atopic allergies. Recommended to stop Ferinject treatment in patients w/ ongoing bacteraemia. Avoid paravenous leakage. In case of paravenous leakage, immediately stop administration. Patients on a Na-controlled diet. Patients w/ liver dysfunction. Avoid parenteral Fe administration in patients w/ hepatic dysfunction where Fe overload is a precipitating factor, in particular porphyria cutanea tarda. Should not be used during pregnancy unless clearly necessary. Treatment w/ Ferinject should be confined to the 2nd & 3rd trimester if the benefit is judged to outweigh the potential risk for both mother & foetus. Not recommended in childn <14 yr.
Adverse Reactions
Nausea, inj/infusion site reactions, hypophosphataemia, headache, flushing, dizziness, HTN.
Drug Interactions
Reduced absorption of oral Fe when co-administered w/ parenteral Fe prep.
MIMS Class
Vitamins & Minerals (Pre & Post Natal) / Antianemics
ATC Classification
B03AC - Iron, parenteral preparations ; Used in the treatment of anemia
Presentation/Packing
Form
Ferinject soln for inj/infusion 500 mg/10 mL
Packing/Price
1's
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