Gynoflor Use In Pregnancy & Lactation

Use in pregnancy: Experiments on animals have shown that estriol has an adverse effect on the foetus. There are no controlled trials on humans. Under these circumstances, Gynoflor should only be used if the potential benefits outweigh the foetal risk.
Due to the facts that Gynoflor contains a very low dose of estriol and that estriol is only minimally absorbed, adverse effects on the foetus when the preparation is used during pregnancy are improbable. In spite of this, Gynoflor should be used for the treatment of vaginal infections or for restoration of the Lactobacillus flora after anti-infective therapy only if such treatment is strictly indicated.
There is no indication for treatment with estriol alone during pregnancy.
Inform the physician if patient becomes pregnant during therapy with Gynoflor.
Use in lactation: There is not enough data on the application of estriol during lactation to be able to estimate possible risks for the newborn infant. However, it is known that estriol enters the mother's milk and can reduce the production of milk. However, considering the low dose and the minimal absorption of estriol after vaginal application, adverse effects on the infant are improbable.