Jardiance Description

JARDIANCE are film-coated tablets for oral administration.
JARDIANCE 10 mg film-coated tablets are pale yellow, round, biconvex and bevel-edged tablets. One side is debossed with the code 'S10', the other side is debossed with the Boehringer Ingelheim company symbol.
JARDIANCE 25 mg film-coated tablets are pale yellow, oval, biconvex tablets. One side is debossed with the code 'S25', the other side is debossed with the Boehringer Ingelheim company symbol.
JARDIANCE 10 mg film-coated tablets contains 10 mg empagliflozin.
JARDIANCE 25 mg film-coated tablets contains 25 mg empagliflozin.
Physicochemical properties: Chemical Structure: Empagliflozin is a white to yellowish powder. It is very slightly soluble in water, slightly soluble in acetonitrile and ethanol, sparingly soluble in methanol and practically insoluble in toluene. Empagliflozin is not hygroscopic and no polymorphism has been observed. It is neither a hydrate nor a solvate. Partition coefficient: log P = log D (pH 7.4): 1.7.
Chemical name: (1S)-1,5-anhydro-1-(4-chloro-3-{4-[(3S)-tetrahydrofuran-3-yloxy]benzyl}phenyl)-D-glucitol.
Molecular formula: C₂₃H₂₇ClO₇.
Molecular weight: 450.91.
CAS number: 864070-44-0.
Excipients with known effect: The JARDIANCE 10 mg tablet contains 162.5 mg of lactose monohydrate and the JARDIANCE 25 mg tablet contains 113 mg of lactose monohydrate per tablet.
Excipients/Inactive Ingredients: Tablet core: lactose monohydrate, microcrystalline cellulose, hydroxypropylcellulose, croscarmellose sodium, colloidal anhydrous silica, magnesium stearate.
Tablet coating: hypromellose, titanium dioxide, purified talc, macrogol 400, iron oxide yellow.