Nitrolingual Dosage/Direction for Use

Dosage guideline: Unless otherwise prescribed, at the start of an angina pectoris attack or immediately before exercise known from experience to be capable of triggering an attack of angina pectoris, depending on the severity, 0.4 mg - 0.8 mg glyceryl trinitrate is administered, corresponding to 1 - 2 puffs of the spray. In patients with acute left-heart failure or acute cardiac infarction, while monitoring the circulatory parameters (systolic blood pressure in excess of 100 mm Hg) 0.4 mg - 1.2 mg glyceryl trinitrate is administered depending on the severity, corresponding to 1 - 3 puffs of the spray. If there is no response after 10 min the treatment may be repeated at the same dose. For prophylaxis prior to coronary angiography, 0.4 mg - 0.8 mg glyceryl trinitrate is administered, corresponding to 1 - 2 puffs of the spray.
Nature and duration of use: Before each use, remove the protective cap by pulling it off in a vertically upward direction. To familiarise oneself with the use of NITROLINGUAL Spray and to fill the dose-metering chamber completely when first using, the valve is first of all operated once and the contents sprayed into the air (press the spray nozzle down smoothly as far as it will go, and then release). This may also be necessary if the spray has not been used for a long time. The spray is now ready to use, and need not be shaken first. When spraying, hold the bottle vertical with the spray nozzle uppermost. Position the orifice in the spray nozzle as close as possible to the mouth. This orifice is easily felt, and can therefore also be used as a reliable indicator of the bottle orientation when using the substance at night. The spray is puffed into the mouth, preferably under the tongue, at intervals of about 30 sec while holding the breath. Do not inhale.