Relenza Dosage/Direction for Use

Inhaled drugs, e.g. asthma medication, should be administered prior to administration of RELENZA (see Precautions).
Treatment of influenza: Treatment should begin as soon as possible, within 48 hours after onset of symptoms for adults, and within 36 hours after onset of symptoms for children.
RELENZA is for administration to the respiratory tract by oral inhalation only, using the DISKHALER device provided. One blister should be utilised for each inhalation.
The recommended dose of RELENZA for treatment of influenza in adults and children from the age of 5 years is two inhalations (2 x 5 mg) twice daily for five days, providing a total daily inhaled dose of 20 mg.
Prevention of influenza: Post-exposure prophylaxis: The recommended dose of RELENZA for prevention of influenza, following close contact with an individual, is two inhalations (2 x 5 mg) once daily for 10 days. Therapy should begin as soon as possible and within 36 hours of exposure to an infected person.
Seasonal prophylaxis: The recommended dose of RELENZA for prevention of influenza during a community outbreak is 2 inhalations (2 x 5 mg) once daily for up to 28 days.
Impaired Renal or Hepatic Function: No dose modification is required. (See Pharmacology: Pharmacokinetics under Actions.)
Older patients: No dose modification is required. (See Pharmacology: Pharmacokinetics under Actions.)