Dosage/Direction for Use
Oral As an antispasmodic Adult: 40-80 mg tid. Child: 1-6 years 20-40 mg 2-3 times daily; >6 years 40 mg tid. |
Administration
May be taken with or without food.
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Special Precautions
Patient with cardiac dysfunction. Renal and hepatic impairment. Children. Pregnancy and lactation. Patient Counselling This drug may occasionally cause vertigo, if affected, do not drive or operate machinery.
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Adverse Reactions
Cardiac disorders: Palpitation.
Gastrointestinal disorders: Gastrointestinal disturbance, nausea, vomiting, constipation, dry mouth.
Nervous system disorders: Vertigo, headache, dizziness.
Psychiatric disorders: Insomnia.
Vascular disorders: Orthostatic hypotension.
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Overdosage
Symptoms: Drowsiness, hypotension, and reduced gastric motility. Management: Symptomatic and supportive treatment.
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Drug Interactions
May attenuate the antiparkinsonian action of levodopa.
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Action
Drotaverine is a musculotropic antispasmodic agent which inhibits phosphodiesterase enzyme, causing increased cAMP levels thereby producing smooth muscle relaxation.
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Storage
Oral: Store below 30°C. Protect from light.
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CIMS Class
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ATC Classification
A03AD02 - drotaverine ; Belongs to the class of papaverine and derivatives. Used in the treatment of functional bowel disorders.
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