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Dosage/Direction for Use
Oral Mild to moderate hypercholesterolaemia Adult: As adjunct to lipid-lowering diet: 7.5-10 g daily. Mix w/ a full glass of liq. Oral Constipation Adult: 3.5 g 1-3 times daily. Mix w/ a full glass of liq. Child: ≤12 yr Each level 5-mL spoonful contains 1.75 g: Half to 1 level 5-mL spoonful bid (morning and evening) to be dissolved in water. |
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Administration
Should be taken with food. Best taken after meals. Stir the required amount into a glass of cold water (150 mL) & drink immediately. Do not take w/o water.
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Contraindications
Pre-existing faecal impaction, intestinal obstruction, natural or drug-induced reduction of gut motility, colonic atony e.g. senile megacolon.
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Special Precautions
Patient w/ swallowing difficulty. Childn.
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Adverse Reactions
Abdominal distention, flatulence, GI impaction, GI obstruction, hypersensitivity reactions e.g. rhinitis, conjunctivitis, bronchospasm and anaphylaxia; cutaneous symptoms (e.g. exanthema and/or pruritus).
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Overdosage
Symptoms: Abdominal discomfort and flatulence. Management: Maintain adequate fluid intake.
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Drug Interactions
May delay or reduce the GI absorption of other drugs e.g. cardiac glycosides, coumarin derivatives, lithium, or vit (e.g. vit B12) and minerals (e.g. Ca, Fe, or Zn).
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Action
Ispaghula husk absorbs water in the GI tract to form a mucilaginous mass which increases faecal mass, thereby promoting peristalsis.
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Storage
Oral: Store below 30°C.
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CIMS Class
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