Sign Out
UserName
Profession Email
Profession Email
|
Dosage/Direction for Use
Oral Psychoses Adult: Acute and chronic psychoses: 400-800 mg daily. May also be given via IM inj. Renal impairment: Dose reduction may be needed. |
|
Contraindications
Comatose states, CNS depression, phaeochromocytoma, porphyria, bradycardia. Lactation.
|
|
Special Precautions
Renal impairment, CV disease, Parkinson's disease, depression. Elderly. May impair ability to drive or operate machinery.
|
|
Adverse Reactions
Extrapyramidal effects, parkinsonian symptoms, dystonia, akathesia, tardive dyskinesia, sleep disturbances, overstimulation, agitation, wt gain, sedation, hyperprolactinaemia.
Potentially Fatal: Ventricular arrhythmia e.g. torsade de pointes, neuroleptic malignant syndrome. |
|
Drug Interactions
Increased risk of ventricular arrhythmia with drugs that prolong QT interval. Increased CNS depression with other CNS depressants e.g. alcohol, general anaesthetics, hypnotics, opioids.
|
|
Action
Sultopride has general properties similar to those of sulpiride. It is a dopamine antagonist and is used in the emergency management of agitation in patients who are psychotic or aggressive and in psychoses e.g. schizophrenia. Given as the hydrochloride but doses are expressed in terms of base. Sultopride hydrochloride 441 mg is equivalent to 400 mg sultopride.
|
|
CIMS Class
|
|
ATC Classification
N05AL02 - sultopride ; Belongs to the class of benzamides antipsychotics.
|
