Candefar Dosage/Direction for Use

Hypertension: The initial dose of Candesartan cilexetil is 4 mg daily. The dose is increased according to the treatment response to a maximum of 16 mg daily. The maximum antihypertensive effect will be achieved within 4 weeks after treatment. Elderly: Adjustment does not need for initial dose if the patient is not over than 75 years old. In patients over 75 years, recommended initial dose is 2 mg once daily and the dose can be increased depends on the clinical response. Patients with renal failure: No dose adjustment is needed if given to patients with mild kidney failure. In patients with moderate and severe kidney failure, it is recommended, administration of Candesartan cilexetil with an initial dose of 2 mg once a day and the dose can be increased according to the response. Patients with liver failure: In patients with mild and moderate liver failure it is recommended that Candesartan cilexetil be given with an initial dose of 2 mg daily, and the dose can be increased according to the response. There is no experience of using Candesartan cilexetil in patients with severe liver disease. Candesartan cilexetil can be given along with other antihypertensive drugs.
Heart Failure: The recommended initial dose is 4 mg daily. The dose increases up to 32 mg once daily or the highest dose that can be tolerated, is done by doubling the dosage with a minimum interval of 2 weeks. Combination therapy: Cilexetil Candesartan can be administered with other heart failure treatments, including ACE inhibitors, beta-blocker, diuretics and digitalis or a combination of these drugs.