Cetrotide Caution For Usage

Cetrotide is for injection under the skin of the lower abdominal wall, preferably around the navel. To minimise local irritation, please select a diff erent injection site each day.
Dissolve Cetrotide only with the water contained in the pre-filled syringe. Do not use Cetrotide solution if it contains particles or if it is not clear.
Before administration, please read the following instructions clearly.
1. Wash hands well with soap and water.
2. On a clean surface, lay out everything needed (1 vial, 1 pre-filled syringe, 1 injection needle with a yellow mark, 1 injection needle with a grey mark and 2 alcohol wipes).
3. Flip off the plastic cover of the vial. Wipe the aluminum ring and the rubber stopper with an alcohol wipe.
4. Take the injection needle with the yellow mark and remove the wrapping. Take the pre-filled syringe and remove the cover. Put the needle on the syringe and remove the cover of the needle.
5. Push the needle through the center of the rubber stopper of the vial. Inject the water into the vial by slowly pushing the plunger of the syringe.
6. Leave the syringe on the vial. Gently shake the vial until the solution is clear and without residue. Avoid forming bubbles during dissolution.
7. Draw the total contents of the vial into the syringe. If liquid is left in the vial, invert the vial, pull back the needle until the opening of the needle is just inside the stopper. Look from the side through the gap in the stopper to control the movement of the needle and the liquid. It is important to withdraw the entire contents of the vial.
8. Detach the syringe from the needle and lay down the syringe. Take the injection needle with the grey mark and remove its wrapping. Put the needle on the syringe and remove the cover of the needle.
9. Invert the syringe and push the plunger until all air bubbles have been pushed out. Do not touch the needle or allow the needle to touch any surface.
10. Choose an injection site at the lower abdominal wall, preferably around the belly button. If on a multiple dose (0.25-mg) regimen, choose a different injection site each day to minimize local irritation. Take the 2nd alcohol wipe, clean the skin at the injection site, and keep the wipe. Hold the syringe in one hand. Gently pinch up the skin surrounding the site of injection and hold firmly with the other hand.
11. Hold the syringe like holding a pencil, insert the needle completely into the skin at an upward angle of about 45°.
12. Once the needle have been inserted completely, release grasp of the skin.
13. Gently pull back the plunger of the syringe to check the correct positioning of the needle. If no blood appears, inject the entire solution by slowly pushing the plunger forward. After all of the solution has been injected, take out the needle at the same angle as it was inserted. Gently press the alcohol wipe on the injection site.
14. If blood appears, withdraw the needle with the syringe and gently press the alcohol wipe on the injection site. Do not use the medicine. Dispose the syringe and the medicine. Use a new packaged tray of Cetrotide to repeat the procedure.
15. Use the syringe and needles only once. Dispose of the syringe and needles immediately after use (put the covers on the needles to avoid injury). If available, a medical waste container should be used for disposal.