Sign Out
IV Drip Infusion: Usual Daily Dosage: Adults: 2-4 g (potency). Children: 100-200 mg (potency)/kg body weight. Both of these are given by IV drip infusion in 2-4 divided doses. Each dose is dissolved in 100-500 mL of IV fluid and infused over a period of 1-2 hrs.
Acute and Elective Abdominal Surgery: Adults and Children >12 years: 8 g as a single dose infused IV 0.5-1 hr preoperative.
Depending on the level of contamination and the length of the surgery, this dose can be repeated. Fosmicin should be given in combination with aerobic antibiotics.
Renal Insufficiency: Repeated doses should not be given if creatinine clearance is <20 mL/min.
The dose interval should be 16 hrs at 20-40 mL/min, Fosmicin 8 mg to be mixed with 500 mL isotonic glucose infusion liquid and to be given at an infusion rate 10-15 mL/min. Heat is generated when Fosmicin is dissolved. Other antibiotics or medicaments should not be added.
