Chemotherapy-induced nausea & vomiting Adult IV Prevention: 1-3 mg by slow IV inj (over 30 sec) or as IV infusion diluted in 20-50 mL of infusion soln for over 5 min before starting chemotherapy. Treatment: 1-3 mg by slow IV inj (over 30 sec) or as IV infusion diluted in 20-50 mL of infusion soln for over 5 min. If necessary, additional dose may be given at least 10 min after the previous administration: Max dose: 9 mg/24 hr.
IM Prevention & treatment: 3 mg 15 min before starting chemotherapy. If necessary, 2 subsequent dose of 3 mg may be given w/in 24 hr.
Childn IV 10-40 mcg/kg diluted in 10-30 mL of infusion soln to be given for 5 min before starting chemotherapy. 1 additional dose may be given at least 10 min after previous administration w/in 24 hr.
RT-induced nausea & vomiting Adult Prevention: 1-3 mg by slow IV inj (over 30 sec) or as IV infusion diluted in 20-50 mL of infusion soln to be given over 5 min before starting RT.
Post-op nausea & vomiting Adult Prevention: 1 mg by slow IV inj (over 30 sec) before anesth induction. Treatment: 1 mg by slow IV inj (over 30 sec). Max: 3 mg IV w/in 1 day for patients before receiving anesth procedure in surgery. Max: 2 doses/day.
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