Fosfomycin trometamol did not adversely influence the pharmacologic effectiveness of commonly prescribed class of drugs: Analgesic (morphine), anticonvulsant (diazepam), bronchodilator (aminophylline), antipyretic (acetaminophen), diuretic (hydrochlorothiazide) and spasmolytic (butylscopolamine).
Concomitant administration of metoclopramide has been shown to lower serum and urinary concentration and should be avoided.