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Niflec should be administered with caution to the following patients: Patients suffering from angina pectoris, myocardial infarction (with the administration of Niflec, the body temperature may decline, that sometimes resulted in chest pain). Patients with renal function disorder (sometimes it may induce nausea).
Basic Important Notes: Mallory Weis Syndrome: Sometimes it may result in Mallory Weis syndrome, tiny holes in the intestinal tract, followed by bleeding, large intestine inflammation, therefore, in administering Niflec, the following must be taken into notice:
Mallory Weis syndrome will appear due to the increasing pressure in the stomach or nausea, therefore avoid administering Niflec within a short period of time (administer Niflec about 1 L/hr).
The contraction in the intestinal tract or the detention of Niflec and the contents of intestines may cause nausea, that will result in such syndromes.
Tiny holes at the intestinal tract and bleeding of the large intestine inflammation are caused by the increasing pressure in the intestinal tract, thus at the time of contraction in the intestinal tract or the detention of remaining food in the intestinal tract, Niflec should be administered with caution.
Niflec is administered after bowel movement on the previous day prior to the administration of Niflec or prior to the administration of Niflec on the same day.
Avoid administering Niflec within a short period of time (administer Niflec about 1 L/hr).
If 1 L has been administered, but there is no bowel movement, first ensure that there is no nausea or abdominal pain before continued administration of Niflec, while monitoring bowel movements.
Caution should be taken in administering Niflec for patients with cavity in the intestinal tract, because development of tiny holes in the intestinal tract has been reported due to the increased pressure in the intestinal tract.
If other ingredients or aromatic materials are added into the solution of Niflec, this will change the osmotic pressure and electrolyte density and it will probably result in inflammable gas produced by bacteria in the intestine, thus such materials are prohibited.
Patients Applying Niflec at Home: The following should be taken notice:
In case of side effect, it will be difficult to handle, thus it is warned not to use Niflec while alone.
Drinking should be done slowly and it is warned to take notice of the initial syndromes of anaphylaxis.
Give detail of the side effects of using Niflec eg, syndromes of the digestive tract (nausea, abdominal pain and others), anaphylactic shock, and it should be warned that in case of any of the syndromes, stop using Niflec and seek medical assistance.
Administration of Niflec to Patient Who Uses Insulin or other Diabetes Drugs: For a patient who controls blood sugar by insulin or other diabetes drug, Niflec should be avoided prior to the day of examination.
Niflec should be given on the day of examination under strict supervision.
Insulin or other diabetes drugs should be administered after meal on the day of examination (because during the period of food control, it is worried that low blood sugar condition may arise).
Effect on Absorption of Other Drugs: Administration of Niflec may probably cause the impediment in absorbing other drugs.
Niflec may also cause problems for patient who takes clinical test, this drugs must be administered in hospital under strict supervision.
Use in pregnancy & lactation: Niflec is only administered to pregnant women or those with pregnancy probability, when it is determined that the advantages in treatment exceed the potential risk. Safety in the administration of Niflec to pregnant women is still uncertain.
Use in children: Safety in the administration of Niflec is still uncertain.
Use in the elderly: In general, the biological function of the elderly has dropped, thus the administration of Niflec must be slowed down. It must be given under strict supervision.
