Plasminex Dosage & Drug Information

Concise Prescribing Info Bahasa Concise Prescribing Info

Concise Prescribing Info

Contents

Tranexamic acid

Indications/Uses

Local fibrinolysis in prostatectomy, epistaxis & canisation of the cervix. Management of dental extraction in haemophiliacs. Hereditary angioneurotic oedema.

Dosage/Direction for Use

FC tab 1 tab 3-4 times daily. Patient w/ renal insufficiency serum creatinine 120-250 micromol/L 15 mg/kg twice daily, 250-500 micromol/L 15 mg/kg 24 hrly, >500 micromol/L 12.5 mg/kg 24 hrly. Inj Local fibrinolysis 500-1,000 mg slow IV 3 times daily. Impaired renal function serum creatinine 120-250 micromol/L 10 mg/kg twice daily, 250-500 micromol/L 10 mg/kg/day, >500 micromol/L 5 mg/kg 24 hrly.

Administration

May be taken with or without food.

Contraindications

Hematuria, disturbances in color vision, high thrombotic risk. Severe renal insufficiency.

Special Precautions

Renal insufficiency, massive haematuria from upper urinary tract. Perform regular eye exam & LFTs in long-term treatment of patients w/ hereditary angioneurotic oedema. Pregnancy & lactation.

Adverse Reactions

Nausea, vomiting, diarrhea, color vision disturbance, hypotension (rapid IV).

View ADR Monitoring Form

Drug Interactions

FC tab: OC containing estrogen. Inj: Soln containing penicillin.

MIMS Class

Haemostatics

ATC Classification

B02AA02 - tranexamic acid ; Belongs to the class of amino acid antifibrinolytics. Used in the treatment of hemorrhage.

Regulatory Classification

Presentation/Packing

Form

Plasminex FC tab 500 mg

Packing/Price

10 × 10's (Rp300,000/boks)

Form

Plasminex inj 100 mg

Packing/Price

5 mL x 10 × 1's (Rp137,500/boks)

Plasminex

tranexamic acid

Manufacturer:

Sanbe