IV bolus inj/continuous infusion Tracheal intubation 0.6 mg/kg.
Rapid sequence induction of anesth 1 mg/kg or 0.6 mg/kg (for those undergoing caesarian section). If 0.6 mg/kg is used, intubate after 90 sec. Maintenance: 0.15 mg/kg.
Long-term inhalation anesth 0.075-0.1 mg/kg.
Continuous infusion Loading dose: 0.6 mg/kg.
Geriatric & patient w/ hepatic &/or biliary tract disease &/or renal failure 0.6 mg/kg. Maintenance: 0.075-0.1 mg/kg. Infusion rate: 0.3-0.4 mg/kg/hr.
Mechanical ventilation Initially 0.6 mg/kg loading dose followed by a continuous infusion as soon as twitch height recovers to 10% or upon re-appearance of 1-2 twitches to train of 4 stimulation. Initial infusion rate for maintenance: 0.3-0.6 mg/kg/hr during the 1st hr, decreased during the following 6-12 hr.