Patients with bronchial asthma or a history of bronchial asthma, bronchospasm, or severe chronic obstructive pulmonary disease [Asthmatic attack may be aggravated or induced due to bronchial smooth muscle contraction caused by β-receptor blockage.].
Patients with poor-controlled cardiac failure, sinus bradycardia, second-or third-degree atrioventricular block, or cardiogenic shock [These symptoms may be aggravated due to negative chronotropic/inotropic effects caused by β-receptor blockage.].
Patients with a history of hypersensitivity to any of the ingredients in this product.