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Aurorix

Aurorix

moclobemide

Manufacturer:

Mylan Healthcare

Distributor:

Zuellig Pharma
Concise Prescribing Info
Contents
Moclobemide
Indications/Uses
Depressive syndromes.
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Dosage/Direction for Use
300-600 mg daily in 2-3 divided doses. Severe depression Initially 300 mg daily, may be increased to 600 mg daily.
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Overdosage
View Aurorix overdosage for action to be taken in the event of an overdose.
Administration
Should be taken with food.
Contraindications
Hypersensitivity. Acute confusional states. Co-administration w/ selegiline, triptans, pethidine, tramadol. bupropion, dextromethorphan, linezolid. Childn.
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Special Precautions
Hypersensitivity. Monitor for clinical worsening, suicidal behaviour or thoughts & unusual changes in behaviour. Depressive patients w/ schizophrenic or schizoaffective psychoses, history of suicide-related events or suicidal ideation. Interrupt treatment if early symptoms of or mania or hypomania occur. Thyrotoxicosis, phaeochromocytoma. Avoid large consumption of tyramine-rich food. Not to be taken by patients w/ galactose intolerance, total lactase deficiency or glucose-galactose malabsorption. Avoid concomitant administration w/ clomipramine. Not recommended in concomitant administration w/ dextromethorphan. Co-administration w/ multi-drug antidepressants; buprenorphine-containing products; serotonergic agents; St. John's wort-containing herbal products. May affect ability to drive & use machines. Hepatic disease. Pregnancy & lactation. Childn & adolescents.
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Adverse Reactions
Sleep disorders; dizziness, headache; dry mouth, nausea. Agitation, anxiety, restlessness; paraesthesia; hypotension; vomiting, diarrhoea, constipation; rash; irritability.
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Drug Interactions
Increased plasma conc of triptans eg, sumatriptan, rizatriptan, zolmitriptan, almotriptan, naratriptan, frovatriptan, eletriptan; PPIs (eg, omeprazole), fluoxetine, fluvoxamine; trimipramine, maprotiline. Potentiated effects of opiates. Serotonin syndrome w/ opioids/opiate products eg, buprenorphine, buprenorphine-containing products; pethidine. Intensified & prolonged action of sympathomimetic agents. Increased CNS serotonin serum conc w/ St. John's wort products. Increased effects w/ sibutramine. Potentiated effects of dextropropoxyphene. Not to be co-administered w/ selegiline, linezolid, tramadol, dextromethorphan. Dose adjustment w/ morphine, fentanyl, codeine; cimetidine. Minor potentiated pressor effect w/ tyramine. Caution w/ antidepressants eg, venlafaxine, clomipramine, citalopram, escitalopram, paroxetine, sertraline, bupropion; TCAs, other antidepressants.
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Caution For Usage
For caution against possible variation of physical aspect of medicine... Click to view Aurorix detailed prescribing information
Storage
View Aurorix storage conditions for details to ensure optimal shelf-life.
Description
View Aurorix description for details of the chemical structure and excipients (inactive components).
Action
View Aurorix mechanism of action for pharmacodynamics and pharmacokinetics details.
MIMS Class
Antidepressants
ATC Classification
N06AG02 - moclobemide ; Belongs to the class of monoamine oxidase A inhibitors. Used in the management of depression.
Presentation/Packing
Form
Aurorix FC tab 150 mg
Packing/Price
100's;30's
Form
Aurorix FC tab 300 mg
Packing/Price
100's;30's
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