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Reconstituted solutions should not be frozen.
Clamentin is less stable in infusions containing glucose, dextran or bicarbonate.
Reconstituted solutions should therefore not be added to such infusions but may be injected into the drip tubing over a period of 3-4 min.
If Clamentin IV is prescribed concurrently with an aminoglycoside, the antibiotics should not be mixed in the syringe, IV fluid container or given set because loss of activity of the aminoglycoside can occur under these conditions.
For storage at 5°C, the reconstituted solution should be added to pre-refrigerated infusion bags which can be stored for up to 8 hrs. Thereafter, the infusion should be administered immediately after reaching room temperature.