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Pregnancy (see also Use in Pregnancy and Lactation).
Bleeding tendency (von Willebrand disease, hemophilia, thrombocytopenia, and platelet function disorders).
Severe hepatic insufficiency and hepatic cirrhosis.
Untreated or uncontrolled hypertension.
Recent intracranial hemorrhage. Other conditions predisposing to intracranial haemorrhage, e.g. aneurysms.
Tendency to fall.
Surgery of the central nervous system or the eye.
Conditions predisposing to the gastrointestinal or urinary tract haemorrhage, e.g. previous gastrointestinal bleeding complications, diverticulosis, or malignancies.
Infectious endocarditis (see also Precautions), pericarditis or pericardial effusion.
Dementia, psychoses, alcoholism, and other situations where compliance may be poor and the treatment cannot be carried out safely in practice.
Hypersensitivity to warfarin or to any of the excipients.
