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Physicochemistry: Nonproprietary name: Sodium Rabeprazole(JAN).
Chemical name: (±)-sodium2-[[4-(3-methoxypropoxy)-3-methylpyridin-2-yl]methylsulfinyl]-1H-benzimidazole.
Molecular formula: C18H20N3O3SNa.
Molecular weight: 381.43.
Sodium rabeprazole occurs as a white to pale yellowish white powder. It is odorless. It is very soluble in water and in methanol, freely soluble in dehydrated ethanol and in ethyl acetate, and practically insoluble in ether and in hexane.
It shows no optical rotation.
It is hygroscopic.
Melting point: 225°C (with decomposition).
Partition coefficient: about 214 (pH7.0, water:octanol).