Verorab

Verorab

rabies vaccine

Manufacturer:

sanofi pasteur

Distributor:

Zuellig Pharma
Concise Prescribing Info
Contents
Purified inactivated rabies vaccine (Wistar rabies PM/WI38 1503-3M strain) prepared on Vero cells
Indications/Uses
Pre- & post-exposure prophylaxis of rabies in all age groups.
Dosage/Direction for Use
Pre-exposure 1 dose IM/ID inj on D0, D7 & D21 or D28 followed by booster dose after 1 yr & subsequent booster dose every 5 yr. Post-exposure Fully immunised patient 1 dose IM inj on D0 & D3. Non-immunised patient Essen regimen: 1 dose IM inj at D0, D3, D7, D14 & D28 or Zagreb regimen: 1 dose IM inj at 2 sites on D0, 1 dose at D7 & D21 or Thai Red Cross regimen: 0.1 mL intradermal inj at 2 sites on D0, D3, D7 & D28.
Contraindications
Pre-exposure: Hypersensitivity to rabies virus, polymyxin B, streptomycin, neomycin or previous inj. Postpone vaccination in case of febrile or acute diseases.
Special Precautions
Known hypersensitivity to polymyxin B, streptomycin, neomycin. Not to be inj intravascularly or into gluteal area; not to be inj intradermally in immunocompromised individuals. Thrombocytopenia, coagulation disorders; anxiety-related reactions eg, syncope, hyperventilation or stress-related reactions; phenylketonuria. Perform blood test 2-4 wk after vaccination in known immunodeficiency due to immunosuppressive disease or concomitant immunosuppressive treatment eg, corticosteroids. May cause allergic reactions due to latex. May affect ability to drive & use machines. Pregnancy. Resp monitoring for 48-72 hr in very premature infants (≤28 gestation wk) & w/ history of resp immaturity.
Adverse Reactions
Headache; myalgia; inj site pain, malaise. Lymphadenopathy; inj site erythema & swelling, fever. Adults: Inj site pruritus & induration, flu-like syndrome. Infants & young childn: Irritability, somnolence; inconsolable crying. Insomnia.
Drug Interactions
Interfered Ab production w/ corticosteroids & immunosuppressives. Not to be administered at same site w/ rabies Ig.
MIMS Class
Vaccines, Antisera & Immunologicals
ATC Classification
J07BG01 - rabies, inactivated, whole virus ; Belongs to the class of rabies viral vaccines.
Presentation/Packing
Form
Verorab powd for susp for inj (vial + solvent in pre-filled syringe)
Packing/Price
0.5 mL x 1's
Register or sign in to continue
Asia's one-stop resource for medical news, clinical reference and education
Already a member? Sign in
Register or sign in to continue
Asia's one-stop resource for medical news, clinical reference and education
Already a member? Sign in