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Zavicefta is a white to yellow sterile powder.
The reconstituted solution is a clear and colourless to yellow solution free from visible particulate matter.
Each vial contains ceftazidime (as pentahydrate) equivalent to 2000 mg ceftazidime and avibactam (as sodium salt) equivalent to 500 mg avibactam.
After reconstitution, 1 mL of solution contains 167.3 mg of ceftazidime (CAZ) and 41.8 mg of avibactam (AVI).
Ceftazidime (as pentahydrate) is a white to almost white crystalline powder. It is soluble in acid, alkali and dimethyl sulphoxide and slightly soluble in water, methanol and dimethylformamide.
Avibactam (as sodium) is a crystalline powder. It is freely soluble in water, relatively soluble in methanol and insoluble in ethanol.
Excipients with known effect: Each vial contains approximately 6.44 mmol of sodium (approximately 148 mg).
Excipient/Inactive Ingredient: Anhydrous sodium carbonate.
