Enhanced hypoprothrombinemic effect & increased risk of bleeding of warfarin & other oral anticoagulants. Enhanced hypoglycemic effect of sulfonylureas (eg, chlorpropamide, tolbutamide). Concomitant w/ corticosteroids may decrease serum salicylate conc. Increased adverse effects (particularly GI & renal effects) w/ NSAIDs. Phenylbutazone, probenecid, sulfinpyrazone; methotrexate.