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The usual dosage for the treatment of osteoporosis in men and women is 10 mg daily. Postmenopausal women may be given 5 mg daily for prophylaxis. It may also be given once weekly to postmenopausal women in a dose of 70 mg for treatment of osteoporosis, or 35 mg for prophylaxis. Men with osteoporosis may be treated with 70 mg once weekly. For the treatment and prevention of corticosteroid-induced osteoporosis a dose of 5 mg daily is given; postmenopausal women who do not take HRT should be given 10 mg daily.
In adults with Paget's disease of bone the usual dose is 40 mg daily for 6 months; treatment may be repeated if necessary after an interval of a further 6 months, or as prescribed by a physician.
