Ursodeoxycholic acid should not be used in patients with: Radio-opaque calcified gall-stones, Acute inflammation of the gall bladder or biliary tract.
Occlusion of the biliary tract (occlusion of the common bile duct or a cystic duct).
Frequent episodes of biliary colic.
Impaired contractability of the gall bladder.
Hypersensitivity to bile acids or any excipients of the formulation.
Who are pregnant or breastfeeding, or in women who may become pregnant.
Chronic liver disease, peptic ulcers or in those with inflammatory disease of the small intestine and colon.