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Use in pregnancy:
Drugs that act directly on the RAAS can cause fetal and neonatal
morbidity and death when administered to pregnant women. When pregnancy
is detected, this combination of losartan and amlodipine should be
discontinued as soon as possible. Oligohydramnios has also been
reported, presumably reporting from decreased fetal renal function.
Use in lactation: It is not known whether losartan or
amlodipine is excreted in human milk. In the absence of this
information, it is recommended that nursing may be discontinued while
the combination is administered.
