As premedicant Adult & childn >20 kg 300-600 mcg SC/IM 30-60 min before anesth or 300-600 mcg IV immediately before anesth. May also be given in combination w/ up to 10 mg morphine sulfate SC/IM about 1 hr before anesth.
Childn up to 3 kg 100 mcg SC/IM;
7-9 kg 200 mcg;
12-16 kg 300 mcg.
Neonate & infant 20 mcg/kg.
Asystole, electromechanical dissociation 1 mg IV repeated every 3-5 min to total of 0.04 mg/kg.
Bradycardia 0.5-1 mg IV repeated every 3-5 min to total of 0.04 mg/kg.
Poisoning w/ other compd having muscarinic actions, organophosphorus pesticides or chemical warfare nerve gases Adult Initially ≥2 mg IM/IV every 10-30 min or every 5 min for severe cases.
Moderate to severe poisoning State of atropinization maintained for at least 2 days.
Overdosage w/ cholinomimetics eg, bethanechol Initially 0.5-1 mg SC/IV & repeated 2 hrly.
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