Aziro-500 Dosage/Direction for Use

The usual oral adult dose of azithromycin is 500 mg as a single dose daily for 3 days. Alternatively, an inital dose of 500 mg may be followed by 250 mg daily for a further 4 days.
For Uncomplicated genital infections caused by Chlamydia trachomatis and for chancroid, 1 g of azithromycin is given as a single dose. A single dose of 2 g has been given for uncomplicated gonorrhea.
For the treatment of granuloma inguinale, an initial dose of 1 g followed by 500 mg daily may be given, or 1 g may be given once a week for at least 3 weeks until all lesions have completely healed.
For prophylaxis of disseminated MAC infections, azithromycin 1.2 g may be given once weekly. For treatment or secondary prophylaxis, 500 mg once daily should be given with other antimycobacterials.
For mild or moderate typhoid caused by multidrug resistant trains, 500 mg once daily may be given for 7 days.
Administration in children: Azithromycin is licensed to use in infants and children and the usual oral dose in those over 6 months of age is 10 mg/kg once daily for 3 days, or an initial dose of 10 mg/kg may be followed by 5 mg/kg daily for a further 4 days, those who weigh over 45 kg may be given the usual adult dose. A single dose of 30 mg/kg may also be given for acute otitis media. For pharyngitis or tonsillitis in children aged over 2 years, 12 mg/kg once daily for 5 days may be given.
For prophylaxis of disseminated Mycobacterium avium complex infections, azithromycin 20 mg/kg (to a maximum of 1.2 g) once weekly or 5 mg/kg (to a maximum of 250 mg once daily may be given.
For treatment, 10 to 12 mg/kg (to a maximum of 500 mg) once daily should be given with other antimycobacterials.
The BNFC suggests that azithromycin may be used in penicillin allergic children for the prevention of secondary cases of group A streptococcal infection, those 6 months and older may be given an oral dose of 12 mg/kg (to a maximum of 500 mg) once daily for 5 days. For the treatment of mild to moderate typhoid caused by multidrug-resistant strains in those aged 6 months and over, azithromycin 10 mg/kg once daily for 7 days.