Bfluid Special Precautions

Careful Administration: Glucose + Amino Acids + Electrolytes + Vitamin B₁ (BFLUID) should be administered with care in the following patients: Patients with hepatic dysfunction. [Abnormalities in water and electrolyte metabolism may be exacerbated.]
Patients with renal dysfunction. [Since these patients have impaired water and electrolyte metabolism, the solution should be administered with care.]
Patients on dialysis or hemofiltration with serious renal disorder, azotemia, or oliguria. [The amounts of water and electrolytes may be excessive and urea and other amino acid metabolites may be retained.] (See Important Precautions as follows.)
Patients with cardiovascular dysfunction. [An increase in the circulating blood volume may cause a burden on the heart, resulting in the patient's clinical condition to deteriorate.]
Patients with acidosis. [The patient's clinical condition may deteriorate.]
Patients with diabetes mellitus. [Impaired uptake of glucose into the tissues may result in hyperglycemia, which may cause the patient's clinical condition to deteriorate.]
Patients with known hypersensitivity to drugs.
Important Precautions: Glucose + Amino Acids + Electrolytes + Vitamin B₁ (BFLUID) contains 15 g of amino acids (2.35 g nitrogen) and 150 kcal (nonprotein calories) in 500 mL. However, daily caloric requirements cannot be met by administering this solution as the sole source of nutritional support. This solution should therefore be used only for short-term nutritional therapy.
When used as a nutritional supplement in patients in whom oral intake is inadequate, the solution should be administered based on an overall assessment of the patient's nutritional requirements and oral intake.
When this solution is used alone in postoperative patients, its use should be limited to 3-5 days and oral/enteral nutrition or other regimens should be instituted as soon as it is feasible to do so.
Glucose + Amino Acids + Electrolytes + Vitamin B₁ (BFLUID) contains 0.96 mg of thiamine chloride hydrochloride (vitamin B₁) as a vitamin source in 500 mL. Additional vitamin B₁ or other vitamins should be administered, depending on the patient's condition.
The volume of water, electrolytes, or urea, etc. removed and acummulated in patients on dialysis or hemofiltration with serious renal disorder, azotemia, or oliguria varies depending on the dialysis method and patient's conditions. Initiation and continuation of administration should be determined after the patient's conditions are carefully checked based on assessment of blood biochemistry, acid-base equilibrium, and body-fluid balance, etc.
Use in Children: The safety of this product in children has not been established (no clinical experience).
Use in the Elderly: Since elderly patients often have reduced physiological function and associated hepatic, renal, or cardiac dysfunction, it is advisable to take measures such as reducing the dose by decreasing the infusion rate under careful supervision.